PALOMA-2 used data from PALOMA-3 to evaluate subcutaneous versus intravenous amivantamab for EGFR-mutated NSCLC. Dr. Ladanyi reflects on genetic hotspot mutations that have not been previously well characterized in lung adenocarcinoma. The study is evaluating regimens to prevent dermatologic adverse events in patients receiving amivantamab plus lazertinib. Final overall survival data from the phase 3 study demonstrated significant benefits for patients with EGFR-mutated aNSCLC. The study authors evaluated the physical, psychosocial, and lifestyle challenges faced by patients with lung cancer. Most patients with MPM experience pleural effusion, but questions remain about the condition's impact on patient outcomes. The NCCN 2025 Annual Conference will be held from March 28-30 in Orlando, Florida. Expanded treatment options for pleural mesothelioma are "urgently needed," due to the high morbidity of the disease. Learn how researchers determined the best treatment strategy for smoking cessation among patients who currently smoke. Clinicians hypothesize that the genetic mutation, known as RUFY1-RET fusion, caused resistance to lorlatinib. A multicenter study that included 21,062 patients who were seen from 2009-2021 in South Korea provided key insights. Dr. Merritt shares new thoracic surgery research insights for patient selection in sublobar resection for early-stage NSCLC. Robert E. Merritt, MD, MBA, FACS, shares insights on his systematic review of sublobar resection and lobectomy. The ORR of the external control group was 3%, while it was 36.8% in those who received amivantamab for NSCLC. Learn how sublobar resection showed "comparable oncologic outcomes and complication rates" as lobectomy per a recent review. For patients with NSCLC and EGFR mutations, amivantamab plus carboplatin-pemetrexed shows OS benefits versus chemo alone. A new study illustrated the importance of exercise for patients with lung cancer who experience cancer-related fatigue. Home-based exercise programs after lung cancer resection do not improve physical function in patients with NSCLC. Implementing pretreatment frailty assessments into clinical workflows may help identify patients at risk of poor outcomes. Researchers evaluated if commercially available AI software was capable of detecting lung cancer in chest radiographs.